Everton were hosed by referee Mark Clattenburg in their rivalry game with Liverpool, but Jay DeMerit and Watford won again to remain atop the second-flight standings.
Blackburn Rovers 4 - 2 Reading
In a battle of American goalkeepers it was Brad Friedel who came out on top after Rovers put four past Marcus Hahnemann to secure all the points in the northwest of England, thanks in part to a pair of goals by Benni McCarthy.
The South African lit up the scoreboard in the 18th minute, shooting from a tight angle, followed by teammate Roque Santa Cruz, getting one for himself after David Dunn played him through to beat Hahnemann low.
The goals continued to come just past the half hour mark when Tugay Kerimoğlu blasted a shot from 30 yards out. Hahnemann was unable to stop what was the eventual game-winner and final goal of the first half.
Steve Coppell brought on two substitutes for the beginning of the second half in Leroy Lita and Brynjar Gunnarsson. With the changes, the Royals settled and were eventually able to get onto the score sheet with a pair of late goals from Kevin Doyle in the 80th and 90th minutes.
McCarthy picked up his second of the afternoon from the penalty spot in the 82nd minute although the contest had been settled long ago.
Bobby Convey did not make the game day roster due to an injured leg.
Next up for Blackburn is a trip to North London to take on underachievers Tottenham, while Reading welcome a fit again Michael Owen and Newcastle United.
Fulham 0 - 0 Derby County
Once again, the Cottagers could only manage a draw as they welcomed bottom dwellers Derby County and let them escape with a share of the points after Fulham played the last 45 minutes a man down after Paul Konchesky's dismissal.
Eddie Lewis played the full 90 for the visitors but his American teammate Benny Feilhaber was nowhere to be found on the game day roster. Carlos Bocanegra came on for the second half to join his international colleague Clint Dempsey, who went the distance.
Kasey Keller was not included on the Fulham bench while Brian McBride is still out through injury.
Antti Niemi was called upon countless times to keep his team in the game, especially after going down to 10 men, although Stephen Bywater was just as busy down the other end, turning away shots. Dempsey had a couple of good efforts saved as well to frustrate Lawrie Sanchez's team, who have drawn half of their league games this season.
The Cottagers will hope to claim the full three points in their next game where they face Sunderland at the Stadium of Light, while the Rams host Tim Howard and Everton at Pride Park.
Everton 1 - 2 Liverpool
Liverpool striker Dirk Kuyt saved the day for the Reds in this hotly contested Merseyside derby.
Luck initially went with the Toffees, as Liverpool's Sami Hyypia attempted a clearance in the 37th minute, but instead sent the shot back into the Redsí net.
Everton's Tony Hibbert was sent off in the 54th minute after bringing down Steven Gerrard in the box. Hibbert, the last defender, was seen by the ref to have knocked Gerrard off balance, resulting in his fall. Kuyt took the penalty that was awarded, sending American keeper Tim Howard the wrong way, equalizing for the Reds.
Referee Mark Clattenburg, who has now been relieved of his duties for this coming weekend due to his controversial decisions at the derby, did not choose to send off Kuyt for a two-footed challenge. Kuyt was instead only booked for the offense.
After quite obviously handling the ball and preventing Liverpool's Lucas from scoring in injury time, Phil Neville was immediately sent off. Kuyt again converted the penalty that was awarded, securing Liverpool's victory.
To add insult to injury, Liverpool defender Jamie Carragher hauled down England international Joleon Lescott in the area, but the infraction went unpunished.
Howard and Everton hope to rebound next Sunday when they travel to Derby.
Watford 1 - 0 Hull City
Jay DeMerit and Watford remained at the top of the League Championship, squeaking past Hull City by a solitary goal.
Jamaican Marlon King scored the game-winner in the 20th minute with a stellar solo effort, dribbling into the area and unloading a right-footed blast past Hull's California-born former England Under-20 keeper Boaz Myhill.
DeMerit went the distance in the victory.
Watford now travel to Coventry City on Tuesday for a midweek contest.
Hereford United 0 - 1 Milton Keynes Dons
Milton Keynes have gone four points clear on the top of the standings of League Two after their ninth win in a row over ten-man Hereford United.
In a fiercely contested first half, Hereford's Stephen Guinan clocked on Lloyd Dyer in the 45th minute and was duly sent off, leaving the guests short a man for the duration of the game.
Nevertheless, they nearly pulled off the short-handed draw. However, late game-winner saved the Dons when midfielder Mark Wright volleyed a headed pass from Aaron Wilbraham past Wayne Brown.
American Jemal Johnson saw action for Milton Keynes off the bench, coming in as 64th-minute substitute for Leon Knight.
The Dons will now take on Stockport County on Saturday as they look to extend their division lead.
Bradford City 0 - 0 Darlington
American Johann Smith started and went 86 minutes in his Darlington debut but was unable to help the Quakers overcome Bradford City.
The best chances of the otherwise drab game came from Irish striker Barry Conlon, who glanced a Paul Heckingbottom serve narrowly wide in the first half.
Bradford defender Darren Williams saved the day for the hosts when he cleared a 55th-minute Greg Blundell shot off the line.
Smith will look to make his home debut on Saturday when the Quakers host fourth place Chesterfield.
Jonathan Spector did not play in West Ham's 3-1 win over Sunderland.
Frank Simek was not ready to return after his ankle injury and did not participate in Sheffield Wednesday's 4-2 road victory over Stoke City.
Cory Gibbs will not return until next season after fracturing three bones in his foot last week. In his stead, Charlton fell 2-0 to Wolverhampton.
Zak Whitbread did not feature in Millwall's 2-1 victory over Bournemouth.